OTHC – 10-Oxo-delta-6a-tetrahydrocannabinol – What We Know About It?

We have a lot of information about the palliative effects of many cannabinoids present in the cannabis sativa that helps in the treatment of cancer-associated symptoms. However, a large body of strong evidence shows that such molecules have the tendency to reduce the tumor growth in several animal models of cancer. This evidence was obtained in the last fifteen years.

Just like cannabinoids and other compounds present in the cannabis sativa, we also have a compound category known as the tetrahydrocannabinol. While we don’t have much information about the medical use of tetrahydrocannabinol, it is certainly one of the most important compounds present in the plant.

Just like tetrahydrocannabinol, different cannabinoids have also shown to activate a more ER-stress related pathway which leads to the stimulation of cancer cell death (autophagy-mediated). In addition to that, cannabinoids decrease cancer cell migration and inhibit tumor angiogenesis.

This mechanism of resistance to the anticancer action of cannabinoid, as well as possible strategies to fully develop combinational cannabinoid-based therapies to fight cancer, has now started to get explored.

OTHC – 10-Oxo-delta-6a-tetrahydrocannabinol and Tetrahydrocannabinol

You must have heard a lot about tetrahydrocannabinol. In fact, we if we talk about marijuana plant, throughout the life, the plant produce more than 400 unique chemical compounds. But there is one compound, among hundreds of them, that has sealed the fate of cannabis for nearly a century.

It is due to this compound that cannabis is now considered the most persecuted compound on this entire planet. This compound is known as tetrahydrocannabinol or THC. There are some other compounds as well that falls within the category of tetrahydrocannabinol and are homologues of tetrahydrocannabinol.

One of these compounds is OTHC – 10-Oxo-delta-6a-tetrahydrocannabinol. Even though due to lack of research work and studies, we don’t have much information about OTHC – 10-Oxo-delta-6a-tetrahydrocannabinol, we know that it belongs to THC by looking at its chemical composition.

In fact, this is the only information we currently have about OTHC – 10-Oxo-delta-6a-tetrahydrocannabinol although it belongs to an important compound category of the plant. Since OTHC – 10-Oxo-delta-6a-tetrahydrocannabinol belongs to the THC category; we can assume that it contains the same effects as that of THC.

But to prove this, we need to conduct more research, probably on mice, and later on clinical trials on human beings to understand its effects on the human body.

Maybe OTHC – 10-Oxo-delta-6a-tetrahydrocannabinol is as psychoactive as THC. Not to mention, years of confusion, questions and misinformation have seriously distorted the understanding of cannabis plant and the psychoactive cannabinoid which makes it the most famous and illicit drug in the entire world.

Whenever any research work is conducted on any compound, the major focus is always to study the medical and recreational uses of that compound. There are many compounds of cannabis which are now being used in different cannabis-based products. However, why many compounds still lack the research work is because of the ongoing legalization issue of marijuana that restricts the research work.

So far, the information about OTHC – 10-Oxo-delta-6a-tetrahydrocannabinol is not enough to establish any idea about its properties. But we hope that further studies will soon be conducted to explore this as well as numerous other undiscovered compounds of cannabis.